• Image courtesy of Dr Kristen Brennand & Dr Fred H. Gage/ Salk Institute for Biological Studies

    human stem cells 2
  • Image courtesy of Dr Yichen Shi and Dr Rick Livesey/ Cambridge Stem Cell Institute

    human stem cells
About EUCelLEX

The European EUCelLEX Project consists in a full examination of the application of the European rules regarding cell banks together with current practices in respect of the therapeutic use of human cells in the different countries concerned. The purpose is to submit the data obtained to the European Commission for it to draw up legislative measures in line with medical advances in this field.
The EUCelLEX project has received funding from the European Union’s FP7 and is coordinated by Emmanuelle RIAL-SEBBAG (Inserm).



from Nature 509,27–28 (01 May 2014) doi:10.1038/509027a

Three independent research teams have now used cloning technology to make human embryonic stem cells carrying the genomes of existing people. The first announcement, using genomes from fetal and infant cells, came last year. The next two reports have emerged in the past month, detailing human embryonic stem cells that were custom made from cell samples derived from living adults, including a 75-year-old man and a 32-year-old woman with type 1 diabetes.

This repeated cloning of embryos and generation of stem cells, now using cells collected from adults, increases the likelihood that human embryos will be produced to generate therapy for a specific individual. The creation of more human embryos for scientific experiments is certain. Regulatory structures must be in place to oversee it.

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from The Welcome Trust Website

Given the potential of stem cell research, a coalition of leading funders of biomedical research, learned societies and patient groups has issued a joint statement calling on the European Parliament to continue funding human embryonic stem cell research.

The statement calls for current provisions that allow for the funding of all types of stem cell research – including human embryonic stem cell research – to be maintained in the EU’s research and innovation programme Horizon 2020.

Read the full statement

in The Journal of Law, Medicine & Ethics – 2014 Volume 42: 1 (ASLME).

Authors : Pascal Borry, Mahsa Shabani, and Heidi Carmen Howard.

In this article, the authors discuss about the right not to know with regard to the increasing availability of genomic testing and consequently the increased possibility of having genomic information processed from minors.

Part of this work is supported by the EUCelLEX project.

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from Nature Medicine 2014 Apr 6. doi: 10.1038/nm.3510.

The team led by Hélène Puccio, director of research for Inserm at the Institute of Genetics and Molecular and Cellular Biology (IGBMC) (Inserm / CNRS / University of Strasbourg) in close collaboration with Patrick Aubourg’s team (Inserm and Professor of Neuropaediatrics at Bicêtre Hospital) has demonstrated, in the mice, the efficacy of gene therapy for treating the heart disease associated with Friedreich’s ataxia, a rare hereditary neuro-degenerative disorder.

The transfer, via a viral vector, of a normal copy of the gene deficient in patients, allowed to fully and very rapidly cure the heart disease in mice.

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from Los Angeles Times

As new revelations further discredit a highly publicized Japanese study on the use of acid to create so-called STAP stem cells, scientists in the U.S. have quietly announced a research breakthrough that involves a more traditional means of producing the amazingly versatile cells.

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